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Miglustat hydrochloride

Cat. No. M10310

All AbMole products are for research use only, cannot be used for human consumption.

Miglustat hydrochloride Structure
Synonym:

OGT 918 HCl; NB-DNJ HCl; Miglustat HCl

Size Price Availability Quantity
5mg USD 98 In stock
10mg USD 170 In stock
25mg USD 340 In stock
50mg USD 560 In stock
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Quality Control & Documentation
Biological Activity

Miglustat hydrochloride also known as OGT 918 and NB-DNJ, inhibits glucosylceramide synthase, and is used primarily to treat Type I Gaucher disease (GD1).

Chemical Information
Molecular Weight 255.74
Formula C10H22ClNO4
CAS Number 210110-90-0
Form Solid
Solubility (25°C) Water 30 mg/mL
DMSO 55 mg/mL
Storage -20°C, sealed
References

[1] Olga Abian, et al. Mol Pharm. Therapeutic strategies for Gaucher disease: miglustat (NB-DNJ) as a pharmacological chaperone for glucocerebrosidase and the different thermostability of velaglucerase alfa and imiglucerase

[2] Paul L M van Giersbergen, et al. J Clin Pharmacol. Influence of food intake on the pharmacokinetics of miglustat, an inhibitor of glucosylceramide synthase

Related Glucosylceramide Synthase Products
Eliglustat

Eliglustat inhibits glucosylceramide synthase (GCS), thus reducing the load of glucosylceramide influx into the lysosome.

Miglustat

Miglustat(OGT918) is an inhibitor of glucosylceramide synthase, primarily to treat Type I Gaucher disease (GD1).

Ibiglustat

Ibiglustat (Venglustat) is a potent and selective Glucosylceramide synthase inhibitor and ceramide glucosyltransferase inhibitor.

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Keywords: Miglustat hydrochloride, OGT 918 HCl; NB-DNJ HCl; Miglustat HCl supplier, Glucosylceramide Synthase, inhibitors, activators

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