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Mefatinib free base

Cat. No. M28751

All AbMole products are for research use only, cannot be used for human consumption.

Mefatinib free base Structure
Synonym:

Mifanertinib

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Quality Control & Documentation
Biological Activity

Mefatinib free base is a potent tyrosine kinase inhibitor with antineoplastic activity.

Chemical Information
Molecular Weight 465.86
Formula C21H19ClF3N5O2
CAS Number 1639014-72-4
Form Solid
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Noemi Reguart, et al. Future Oncol. Common EGFR-mutated subgroups (Del19/L858R) in advanced non-small-cell lung cancer: chasing better outcomes with tyrosine kinase inhibitors

[2] T Brown, et al. Health Technol Assess. Gefitinib for the first-line treatment of locally advanced or metastatic non-small cell lung cancer

[3] Kiyohiko Sugano. Int J Pharm. Computational oral absorption simulation of free base drugs

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Keywords: Mefatinib free base, Mifanertinib supplier, c-Met, inhibitors, activators

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