All AbMole products are for research use only, cannot be used for human consumption.
MI-136 inhibits DHT-induced expression of androgen receptor (AR) target genes. MI-136 treatment inhibits the expression of genes that were bound to ASH2L after AR stimulation.
In vivo, treatment of VCaP tumor-bearing mice with MI-136 (40 mg/kg) led to a modest but significant reduction in tumor volume with no effect on mouse body weight.
| Molecular Weight | 470.51 |
| Formula | C23H21F3N6S |
| CAS Number | 1628316-74-4 |
| Solubility (25°C) | DMSO: ≥ 30 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Related Androgen Receptor Products |
|---|
| MDV3100
MDV3100 is an orally bioavailable, organic, non-steroidal small molecule targeting the androgen receptor (AR) with potential antineoplastic activity. |
| Bicalutamide
Bicalutamide is an orally active non-steroidal androgen receptor antagonist (IC50 = 190 nM). |
| Ostarine
Ostarine (GTx-024 and MK-2866) is an investigational selective androgen receptor modulator (SARM) with Ki of 3.8 nM. |
| Andarine
Andarine (GTx-007, S-4) is a selective nonsteroidal androgen receptor (AR) agonist with Ki of 4 nM. |
| AZD3514
AZD3514 is a potent, orally activie and selective androgen receptor (AR) inhibitor with potential anticancer cancer activity. |
All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.
Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2026 AbMole BioScience. All Rights Reserved.
