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MF498

Cat. No. M10856

All AbMole products are for research use only, cannot be used for human consumption.

MF498  Structure

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Quality Control & Documentation
Biological Activity

MF498 is a novel selective prostaglandin E4 receptor (EP4 receptor) antagonist with a strong affinity with the EP4 receptor, with a Ki of 0.7 nM.

Chemical Information
Molecular Weight 603.69
Formula C32H33N3O7S
CAS Number 915191-42-3
Solubility (25°C) DMSO ≥ 20 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Patsy Clark, et al. J Pharmacol Exp Ther. MF498 [N-{[4-(5,9-Diethoxy-6-oxo-6,8-dihydro-7H-pyrrolo[3,4-g]quinolin-7-yl)-3-methylbenzyl]sulfonyl}-2-(2-methoxyphenyl)acetamide], a selective E prostanoid receptor 4 antagonist, relieves joint inflammation and pain in rodent models of rheumatoid and os䲧璷Ỵ璸㧀璶

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Keywords: MF498 supplier, Prostaglandin Receptor, inhibitors, activators

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