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Methylprednisolone sodium succinate

Cat. No. M25573

All AbMole products are for research use only, cannot be used for human consumption.

Methylprednisolone sodium succinate Structure
Synonym:

6α-Methylprednisolone 21-hemisuccinate sodium

Size Price Availability Quantity
10mg USD 40 In stock
50mg USD 120 In stock
100mg USD 180 In stock
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Quality Control & Documentation
Biological Activity

Methylprednisolone sodium succinate is a glucocorticoid receptor agonist with immunosuppressive and anti-inflammatory activity that can be converted to active prednisolone in vivo, thereby activating GR-mediated gene expression. In addition, Methylprednisolone sodium succinate can be used to construct a rat model of hormonal femoral head necrosis.

Chemical Information
Molecular Weight 496.5
Formula C26H33NaO8
CAS Number 2375-03-3
Form Solid
Solubility (25°C) Water 50 mg/mL (ultrasonic)
DMSO 25 mg/mL
Storage 4°C, dry, sealed
References

[1] Zhilei Guo, et al. Medicine (Baltimore). Compatibility and stability of methylprednisolone sodium succinate and granisetron hydrochloride in 0.9% sodium chloride solution

[2] Foteini Stefania Koumpa, et al. BMJ Case Rep. Sudden irreversible hearing loss post COVID-19

[3] Chen Peng, et al. Eur J Hosp Pharm. Compatible stability of methylprednisolone sodium succinate and tropisetron in 0.9% sodium chloride injection

[4] Shiqi Cheng, et al. Brain Res Bull. Methylprednisolone sodium succinate reduces BBB disruption and inflammation in a model mouse of intracranial haemorrhage

[5] P L Toutain, et al. J Pharm Sci. Pharmacokinetics of methylprednisolone, methylprednisolone sodium succinate, and methylprednisolone acetate in dogs

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Keywords: Methylprednisolone sodium succinate, 6α-Methylprednisolone 21-hemisuccinate sodium supplier, Animal Modeling, inhibitors, activators

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