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Methylophiopogonanone B

Cat. No. M10978

All AbMole products are for research use only, cannot be used for human consumption.

Methylophiopogonanone B  Structure
Size Price Availability Quantity
2mg USD 120 In stock
5mg USD 200 In stock
10mg USD 325 In stock
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Quality Control & Documentation
Biological Activity

Methylophiopogonanone B, high isotinodihydroflavones, extracted from the roots of Wheat Dong, has a high antioxidant capacity. Methylophiopogonanone B increases GTP-Rho and works through the Rho signaling pathway, and Methylophiopogonanone B induces changes in cell morphology, including dendritic contraction and stress fiber formation, through actin cytoskeletal recombination.

Chemical Information
Molecular Weight 328.36
Formula C19H20O5
CAS Number 74805-91-7
Form Solid
Solubility (25°C) DMSO ≥ 60 mg/mL
Storage 4°C, protect from light, dry, sealed
References

[1] YuShan Tian, et al. J Ethnopharmacol. Investigation of the effective components inhibited macrophage foam cell formation in Ophiopogonis Radix

[2] Lingna Wu, et al. Biomed Pharmacother. Interactions of the major effective components in Shengmai formula with breast cancer resistance protein at the cellular and vesicular levels

[3] Liling Wang, et al. Mol Med Rep. Methylophiopogonanone B of Radix Ophiopogonis protects cells from H2O2‑induced apoptosis through the NADPH oxidase pathway in HUVECs

[4] Yuko Ito, et al. Mol Cell Biochem. A novel agent, methylophiopogonanone B, promotes Rho activation and tubulin depolymerization

[5] Y Ito, et al. J Dermatol Sci. Effects of methylophiopogonanone B on melanosome transfer and dendrite retraction

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Keywords: Methylophiopogonanone B supplier, Ras, inhibitors, activators

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