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Metergoline is a serotonin (5-HT) receptor and dopamine receptors antagonist, with pKis of 8.64, 8.75 and 8.75 for 5-HT2A, 5-HT2B and 5-HT2C, respectively. Metergoline is a high-affinity ligand for the h5-HT7 receptor, with a Ki of 16 nM. Metergoline is also a reversible neural Na+ channels inhibitor.
| Molecular Weight | 403.52 |
| Formula | C25H29N3O2 |
| CAS Number | 17692-51-2 |
| Solubility (25°C) | DMSO 45 mg/mL |
| Storage | Powder -20°C |
[3] Kai Kang, et al. Metergoline-induced cell death in Candida krusei
[4] A Caballero Sr, et al. Metergoline as a lactation inhibitor
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