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Meta-Fexofenadine

Cat. No. M6111

All AbMole products are for research use only, cannot be used for human consumption.

Meta-Fexofenadine Structure
Size Price Availability Quantity
5mg USD 320 In stock
10mg USD 550 In stock
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Quality Control & Documentation
Biological Activity

Meta -Fexofenadine (META -MDL-16455) is an impurity of Fexofenadine.

Protocol (for reference only)
Cell Experiment
Cell lines The human epithelial cells COLO205
Preparation method Cells were pretreated with various concentrations of fexofenadine or with PBS and were stimulated with TNF-α.
Concentrations 50 μM
Incubation time 90 min
Animal Experiment
Animal models Male Wistar rats
Formulation pH 7.4 isotonic Dulbecco’s PBS (D-PBS) containing 25 mM glucose
Dosages 10 mg/ kg
Administration orally
Chemical Information
Molecular Weight 501.66
Formula C32H39NO4
CAS Number 479035-75-1
Solubility (25°C) 10 mM in DMSO
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Neerati P, et al. Pharmacol Rep. Effect of diosmin on the intestinal absorption and pharmacokinetics of fexofenadine in rats.

[2] Koh SJ, et al. J Pharmacol Exp Ther. Fexofenadine regulates nuclear factor-κB signaling and endoplasmic reticulum stress in intestinal epithelial cells and ameliorates acute and chronic colitis in mice.

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Keywords: Meta-Fexofenadine supplier, Histamine Receptor, inhibitors, activators

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