All AbMole products are for research use only, cannot be used for human consumption.
Met-Arg-Phe-Ala (MRFA) is a peptide. MRFA is used as a calibration standard in mass spectrometry (ESI). MRFA has been shown to be a competitive inhibitor of an enkephalin-generating endopeptidase isolated from rat brain. Met-Arg-Phe-Ala can be used for the research of neurological disease.
| Molecular Weight | 523.65 |
| Formula | C23H37N7O5S |
| CAS Number | 67368-29-0 |
| Form | Powder |
| Solubility (25°C) | DMSO ≥ 50 mg/mL |
| Storage | -20°C, dry, sealed |
| Related Neprilysin (NEP) Products |
|---|
| Racecadotril
Racecadotril is a peripheral enkephalinase inhibitor with an IC50 of 4.5 μM.Racecadotril and its active metabolite, Thiorphan, inhibited the activity of purified NEP in the mouse brain with Ki's of 4500 and 6.1 nM.May be used in diarrhea related studies. |
| AHU-377 hemicalcium salt
AHU-377 hemicalcium salt is a potent NEP inhibitor with an IC50 of 5 nM. AHU-377 is a component of the heart failure medicine LCZ696. |
| Phosphoramidon disodium salt
Phosphoramidon disodium salt is a microbial metabolite and an inhibitor of the specific metalloproteases thermolysin, endothelin-converting enzyme (ECE), neutralizing peptidase (NEP) and angiotensin-converting enzyme (ACE), with IC50s of 0.4 μg/mL, 3.5 μM, 0.034 μM and 78 μM, respectively. Phosphoramidon disodium salt also prevented the degradation of amyloid β-peptide and increased Aβ levels in rodents. |
| Sacubitrilat
Sacubitrilat (LBQ-657) is an active metabolite of Sacubitril and an inhibitor of enkephalinase (NEP). |
| Sacubitril
Sacubitril (AHU-377) is a potent NEP inhibitor with an IC50 of 5 nM. Sacubitril (AHU-377) is a component of the heart failure medicine LCZ696. |
All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.
Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2026 AbMole BioScience. All Rights Reserved.
