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Meropenem (SM 7338) trihydrate is a carbapenem antibiotic, which displaying a broad spectrum of antibacterial activity. Meropenem trihydrate has activity against susceptible and resistant N. gonorrhoeae (MIC value of 0.02-0.06 mg/mL), H. influenzae (MIC value of 0.03-0.12 mg/mL), and H. ducreyi (MIC value of 0.015-0.12 mg/mL).
Meropenem (60 mg/kg; intraperitoneal injection; once) treatment significantly reduces the incidence of pancreatic infection in SD rats.
| Molecular Weight | 437.51 |
| Formula | C17H31N3O8S |
| CAS Number | 119478-56-7 |
| Solubility (25°C) | DMSO 90 mg/mL Water 10 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
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