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MEK inhibitor is a potent MEK inhibitor with antitumor potency.
| Molecular Weight | 426.51 |
| CAS Number | 334951-92-7 |
| Solubility (25°C) | DMSO 50 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[1] Kata Czirbesz, et al. [BRAF-MEK inhibitor therapy in melanoma]
[3] Chao Wang, et al. Hybrids of MEK inhibitor and NO donor as multitarget antitumor drugs
[4] Ufuk Degirmenci, et al. Targeting Aberrant RAS/RAF/MEK/ERK Signaling for Cancer Therapy
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ARRY-162 (MEK-162; Binimetinib) is a selective, potent inhibitor of MEK and cellular pERK with IC50 of 12 nM and 11 nM, respectively. |
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