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Noncompetitive nicotinic acetylcholine receptor antagonist; preferentially blocks nicotinic receptors at autonomic ganglia; crosses blood-brain barrier.
Cell Stem Cell. 2025 Nov 07; .
Generation of human nucleus basalis organoids with functional nbM-cortical cholinergic projections in transplanted assembloids.
Mecamylamine hydrochloride purchased from AbMole
| Molecular Weight | 203.75 |
| Formula | C11H21N · HCl |
| CAS Number | 826-39-1 |
| Form | Solid |
| Solubility (25°C) | Water ≥ 50 mg/mL Ethanol 40 mg/mL DMSO 22 mg/mL |
| Storage | 4°C, dry, sealed |
[2] Justin R Nickell, et al. Potential therapeutic uses of mecamylamine and its stereoisomers
[3] No authors listed. J Am Med Assoc. MECAMYLAMINE hydrochloride
[4] J E BAER, et al. Renal elimination of 3-methylaminoisocamphane hydrochloride (mecamylamine)
[5] J M Young, et al. Mecamylamine: new therapeutic uses and toxicity/risk profile
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