Free shipping on all orders over $ 500

ME1111 

Cat. No. M28312

All AbMole products are for research use only, cannot be used for human consumption.

ME1111  Structure

Price and Availability

For this product's availability, delivery time and price, please email inquiry@abmole.com directly or click the "Inquiry Now" button below.


Quality Control & Documentation
Biological Activity

ME1111 is an antifungal agent that is active against dermatophytes. ME1111 is an inhibitor of the succinate dehydrogenase of Trichophyton species. ME1111 has an excellent ability to penetrate human nails and is used for onychomycosis research.

Chemical Information
Molecular Weight 202.25
Formula C12H14N2O
CAS Number 1391758-52-3
Form Solid
Solubility (25°C) DMSO 100 mg/mL (ultrasonic)
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Natsuki Kubota-Ishida, et al. Antimicrob Agents Chemother. In Vitro Human Onychopharmacokinetic and Pharmacodynamic Analyses of ME1111, a New Topical Agent for Onychomycosis

[2] Xiaoying Hui, et al. Drug Dev Ind Pharm. Antifungal ME1111 in vitro human onychopharmacokinetics

[3] L Long, et al. Antimicrob Agents Chemother. Evaluation of the Efficacy of ME1111 in the Topical Treatment of Dermatophytosis in a Guinea Pig Model

[4] Sho Takahata, et al. Antimicrob Agents Chemother. Mechanism of Action of ME1111, a Novel Antifungal Agent for Topical Treatment of Onychomycosis

Related Antifungal Products
2-Phenylethyl isothiocyanate

2-Phenylethyl isothiocyanate is a natural product found in bean sprouts and cruciferous vegetables, and is also an effective antifungal agent, significantly inhibiting spore germination and mycelial growth of Aspergillus intermedius. In addition, 2-Phenylethyl isothiocyanate induces autophagy and inhibits the growth of various tumor cells.

Mutanocyclin

Mutanocyclin, a tetramic acids analog, is also a potent antifungal agent that inhibits mycelium formation in Candida albicans. In addition, Mutanocyclin also reduces the mRNA expression of HWP1, ECE1, FLO8, TEC1, and has inhibitory activity against immune cell infiltration.

2-O-Methylanigorufone

2-O-Methylanigorufone (Methoxyanigorufone) is a natural product which can be from Monochoria vaginalis or Musa acuminata.

Xanthoxylin

Xanthoxylin has antifungal and antispasmodic activities. Xanthoxylin is isolated from Zanthoxylum simulans.

2-Hydroxy-1,4-naphoquinone

2-Hydroxy-1,4-naphoquinone

  Catalog
Abmole Inhibitor Catalog




Keywords: ME1111  supplier, Antifungal, inhibitors, activators

All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.



Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2026 AbMole BioScience. All Rights Reserved.