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MDL 28170

Cat. No. M7934

All AbMole products are for research use only, cannot be used for human consumption.

MDL 28170 Structure
Synonym:

Calpain Inhibitor III

Size Price Availability Quantity
2mg USD 40 In stock
5mg USD 70 In stock
10mg USD 100 In stock
25mg USD 190 In stock
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Quality Control & Documentation
Biological Activity

Mdl-28170 (Calpain Inhibitor III) is a potent, selective, membrane-permeable Inhibitor of cysteine protease (Calpain Inhibitor III) that can quickly cross the blood-brain barrier after systemic administration. Mdl-28170 also blocks gamma-secretase.

Product Citations
Chemical Information
Molecular Weight 382.45
Formula C22H26N2O4
CAS Number 88191-84-8
Solubility (25°C) DMSO: 24 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Kharatmal SB, et al. Neuropharmacology. Calpain inhibitor, MDL 28170 confer electrophysiological, nociceptive and biochemical improvement in diabetic neuropathy.

[2] Ai J, et al. J Neurotrauma. Calpain inhibitor MDL-28170 reduces the functional and structural deterioration of corpus callosum following fluid percussion injury.

[3] Li PA, et al. Neurosci Lett. Postischemic treatment with calpain inhibitor MDL 28170 ameliorates brain damage in a gerbil model of global ischemia.

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Keywords: MDL 28170, Calpain Inhibitor III supplier, Gamma-secretase/Beta-secretase, inhibitors, activators

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