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MCL0020

Cat. No. M53081

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MCL0020 Structure

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Quality Control & Documentation
Biological Activity

MCL0020 is a potent and selective melanocortin MC4 receptor antagonist, with an IC50 of 11.63 nM.

Chemical Information
Molecular Weight 609.72
Formula C34H39N7O4
CAS Number 475498-26-1
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Related Melanocortin Receptor Products
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α-MSH (α-Melanocyte-stimulating hormone) is a tridecapeptide, mostly produced by the cells in the brain, pituitary and circulation.

Melanotan I acetate

Melanotan I acetate is a synthetic analogue of α-melanocyte stimulating hormone (α-MSH). *This compound is unstable in solutions, freshly prepared is recommended.

Setmelanotide

Setmelanotide is a selective agonist of the MC4 receptor, with EC50 values of 0.27 nM and 0.28 nM for human and rat MC4R, respectively.

Bremelanotide Acetate

Bremelanotide Acetate (PT-141 Acetate) is a peptide containing seven amino acids and is also a macrocyclic compound. In addition, Bremelanotide Acetate is an agonist of the melanocortin 4 receptor (MC4R).

JNJ-10229570

JNJ-10229570 (UNII-N9IX402L35) is is a novel MC1R and MC5R antagonist, which inhibits the binding of 125I-NDP-α-MSH to cells expressing human MC1R and MC5R with IC50 values of 270 nM and 200 nM, respectively.

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Abmole Inhibitor Catalog




Keywords: MCL0020 supplier, Melanocortin Receptor, inhibitors, activators

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