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MC-SN38 is a agent-linker conjugate composed of a potent microtubule-disrupting agent SN38 and a non-cleavable MC linker to make antibody agent conjugate (ADC).
| Molecular Weight | 585.6 |
| Formula | C32H31N3O8 |
| CAS Number | 1473403-87-0 |
| Form | Solid |
| Solubility (25°C) | DMSO 100 mg/mL |
| Storage | Powder -20°C |
| Related Drug-Linker Conjugates for ADC Products |
|---|
| Mc-Val-Cit-PABC-PNP
Mc-Val-Cit-PABC-PNP is a histone-cleavable peptide linker for antibody-drug couplings (ADCs) that can be used for the synthesis of ADCs such as Brentuximab vedotin. |
| DM1-SMCC
DM1-SMCC is DM1 with a reactive linker SMCC, which can react with antibody to make ADC. |
| CL2A-SN-38
CL2A-SN-38 is a SN38 derivative with a peptide-linker which can easily react with antibody to form an ADC. |
| BS3 (bis(sulfosuccinimidyl)suberate)
BS3 (bis(sulfosuccinimidyl)suberate) is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). |
| Sulfo-SMCC sodium
Sulfo-SMCC sodium is a commonly used hetero-bifunctional, noncleavable ADC crosslinker bearing N-hydroxysuccinimide (NHS) ester and maleimide groups to react with primary amines and sulfhydryl groups, respectively. |
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