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MBX2329 

Cat. No. M28437

All AbMole products are for research use only, cannot be used for human consumption.

MBX2329  Structure

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Quality Control & Documentation
Biological Activity

MBX2329, a potent influenza virus inhibitor, specifically inhibits hemagglutinin (HA)-mediated viral entry with HIV/HA(H5) displaying IC90 of 8.6 μM. MBX2329 inhibits a wide spectrum of influenza A viruses, which includes the 2009 pandemic influenza virus A/H1N1/2009, highly pathogenic avian influenza (HPAI) virus A/H5N1, and oseltamivir-resistant A/H1N1 strains.

Chemical Information
Molecular Weight 283.84
Formula C16H26ClNO
CAS Number 1438272-42-4
Form Solid
Solubility (25°C) DMSO 250 mg/mL (ultrasonic)
Storage 4°C, dry, sealed
References

[1] Shanshan Guan, et al. Sci Rep. Exploration of binding and inhibition mechanism of a small molecule inhibitor of influenza virus H1N1 hemagglutinin by molecular dynamics simulation

[2] Aleksandar Antanasijevic, et al. J Biol Chem. Mutagenesis studies of the H5 influenza hemagglutinin stem loop region

[3] Arnab Basu, et al. J Virol. New small molecule entry inhibitors targeting hemagglutinin-mediated influenza a virus fusion

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  Catalog
Abmole Inhibitor Catalog




Keywords: MBX2329  supplier, Anti-infection, inhibitors, activators

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