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MB-07811 (VK2809) is an orally active, thyroid hormone receptor (THR)-beta agonist that can be used in studies related to hyperlipidemia and nonalcoholic steatohepatitis (NASH).
| Molecular Weight | 514.98 |
| Formula | C28H32ClO5P |
| CAS Number | 852948-13-1 |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Related Thyroid Hormone Receptor Products |
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| Liothyronine Sodium
Liothyronine Sodium is the most potent form of thyroid hormone acting on the body to increase the basal metabolic rate, affect protein synthesis. Liothyronine sodium is a potent thyroid hormone receptors TRα and TRβ agonist with Kis of 2.33 nM for hTRα and hTRβ, respectively. |
| Tiratricol
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| Resmetirom (MGL-3196)
Resmetirom (MGL-3196, VIA-3196, resmetirom) is a potentially first-in-class, liver-targeted, orally active, selective thyroid hormone receptor (THR)-β agonist with an EC50 value of 0.21 μM. Resmetirom avoids the activation of THR-α receptors that mediate thyroid hormone activity outside of the liver, including the heart and bone. Resmetirom avoids the activation of THR-α receptors that mediate extrahepatic (including cardiac and skeletal) thyroid hormone activity and can be used in studies of non-alcoholic steatohepatitis (NASH). |
| L-Thyroxine sodium salt pentahydrate
L-thyroxine sodium salt pentahydrate (L-thyroxine sodium pentahydrate; Levothyroxine, both found to lower total and LDL cholesterol levels. L-Thyroxine sodium salt pentahydrate (Levothyroxine; T4) is a synthetic thyroid hormone used in the study of hypothyroidism. |
| Octinoxate
Octinoxate is an organic compound that is an ingredient in some sunscreens and lip balms, primarily used is in sunscreens and other cosmetics to absorb UV-B rays from the sun, protecting the skin from damage. It is also used to reduce the appearance of scars. |
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