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Mavrilimumab

Cat. No. M24547

All AbMole products are for research use only, cannot be used for human consumption.

Mavrilimumab Structure
Synonym:

CAM 3001

Size Price Availability Quantity
100ug USD 180 In stock
1mg USD 350 In stock
5mg USD 720 In stock
Free Delivery on orders over USD 500 Bulk Inquiry?

Quality Control & Documentation
Biological Activity

Mavrilimumab (CAM 3001) is a monoclonal antibody that binds to the α subunit of the granulocyte-macrophage colony stimulating factor (GM-CSF) receptor and blocks intracellular signalling downstream of GM-CSF. GM-CSF might be a mediator of the hyperactive inflammatory response associated with respiratory failure and death.

Chemical Information
CAS Number 1085337-57-0
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
References

[1] Maria C Cid, et al. Ann Rheum Dis. Efficacy and safety of mavrilimumab in giant cell arteritis: a phase 2, randomised, double-blind, placebo-controlled trial

[2] Mohamad Amin Pourhoseingholi, et al. Lancet Rheumatol. Mavrilimumab for severe COVID-19

[3] Adil Rashid Khan, et al. Lancet Rheumatol. Mavrilimumab for severe COVID-19

[4] Chiara Crotti, et al. Expert Opin Investig Drugs. Mavrilimumab: a unique insight and update on the current status in the treatment of rheumatoid arthritis

[5] Manuela Di Franco, et al. Core Evid. Mavrilimumab: an evidence based review of its potential in the treatment of rheumatoid arthritis

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Keywords: Mavrilimumab, CAM 3001 supplier, CSF-1R (c-Fms), inhibitors, activators

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