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MAT2A Allosteric inhibitor 2 is a potent and selective MAT2A allosteric inhibitor with an IC50 of 5 nM.
| Molecular Weight | 319.35 |
| Formula | C20H17NO3 |
| CAS Number | 631897-75-1 |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Related Methionine Adenosyltransferase Products |
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| PF-9366
PF-9366 is a novel inhibitor of human methionine adenosyltransferase 2A (Mat2A), with IC50 of 420 nM and Kd of 170 nM. |
| FIDAS-5
FIDAS-5 is a potent and orally active methionine S-adenosyltransferase 2A (MAT2A) inhibitor with an IC50 of 2.1 μM. |
| AG-270
AG-270 is a non-competitive, first-of-its-kind, reversible, orally active MAT2A allogeneic inhibitor IC50 The value is 14 nM. |
| IDE397
IDE397 (GSK-4362676) is a potent, potential "first-in-class" inhibitor of methionine adenosyltransferase 2A (MAT2A). IDE397 (GSK-4362676) exhibits anti-tumor activity in MTAP-deleted PDX models. |
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