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Maprotiline hydrochloride is a selective noradrenalin re-uptake inhibitor and a tetracyclic antidepressant. Maprotiline hydrochloride acts primarily by potentiation of central adrenergic synapses by blocking reuptake of norepinephrine at nerve endings. Maprotiline hydrochloride is indicated for the treatment of depressive illness in patients with depressive neurosis (dysthymic disorder) and manic-depressive illness, depressed type (major depressive disorder). Maprotiline hydrochloride is also effective for the relief of anxiety associated with depression.
| Molecular Weight | 313.86 |
| Formula | C20H23N.HCl |
| CAS Number | 10347-81-6 |
| Solubility (25°C) | DMSO 60 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
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