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Malotilate

Cat. No. M2222

All AbMole products are for research use only, cannot be used for human consumption.

Malotilate Structure
Synonym:

NKK 105

Size Price Availability Quantity
10mg USD 85 In stock
50mg USD 145 In stock
100mg USD 240 In stock
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Quality Control & Documentation
Biological Activity

Malotilate is a hepatoprotective agent used in the treatment of liver disease. Malotilate accelerates the recovery of impaired protein metabolism in alcoholic liver disease. It has been shown to facilitate liver regeneration in rats.

Chemical Information
Molecular Weight 288.38
Formula C12H16O4S2
CAS Number 59937-28-9
Form Solid
Solubility (25°C) DMSO 50 mg/mL
Ethanol 50 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] P R Ryle, et al. Malotilate: the new hope for a clinically effective agent for the treatment of liver disease

[2] Y Matsuda, et al. Effects of malotilate on alcoholic liver injury in rats

[3] M Itakura, et al. Malotilate (diisopropyl 1,3-dithiol-2-ylidenemalonate) increases liver de novo purine synthesis and amidophosphoribosyltransferase activity

[4] S Takase, et al. Effects of malotilate treatment on alcoholic liver disease

[5] F Nomura, et al. Detection of malotilate toxicity in vitro with peripheral blood mononuclear cells as targets. A preliminary report

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Keywords: Malotilate, NKK 105 supplier, Lipoxygenase, inhibitors, activators

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