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Maleimido-mono-amide-DOTA is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
| Molecular Weight | 786.5 |
| Formula | C22H34N6O9.HPF₆.TFA |
| CAS Number | 1006711-90-5 (free base) |
| Solubility (25°C) | Water 90 mg/mL DMSO 90 mg/mL |
| Storage | -20°C, protect from light, dry, sealed |
[2] Kam Leung. N-[2-(4-[18F]Fluorobenzamido)ethyl]maleimide-Cys-ZEGFR:1907
| Related ADC Linker Products |
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| 6-Maleimidohexanoic acid N-hydroxysuccinimide ester
6-Maleimidohexanoic acid N-hydroxysuccinimide ester(ECMS) is a useful protective group in antibody drug conjugates. |
| Sulfo-NHS
Sulfo-NHS is a peptide condensing agent, can form a stable active ester intermediate, used to prepare hydrophilic active ester, for example as a protein cross-linking agent. N-Hydroxysulfosuccinimide (sodium) is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). |
| SPDP Crosslinker
SPDP crosslinker, or SPDP NHS ester, is a cleavable, water insoluble, amino and thiol (sulfhydryl) reactive heterobifunctional protein crosslinker. *The compound is unstable in solutions, freshly prepared is recommended |
| Mc-Val-Cit-PAB
Mc-Val-Cit-PAB is a peptide linker molecule used in the synthesis of antibody-drug conjugates (ADCs). |
| Fmoc-Val-Cit-PAB
Fmoc-Val-Cit-PAB-OH is a cleavable useful heterobifunational linker for making Antibody-Drug-Conjugates (ADC). |
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