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MAGL-IN-5 (CAY10499) is a non-selective lipase inhibitor with IC50 values of 144, 90, and 14 nM for human recombinant monoacylglycerol lipase(MAGL),hormone sensitive lipase(HSL), and fatty acid amide hydrolase(FAAH) respectively.
| Molecular Weight | 355.34 |
| Formula | C18H17N3O5 |
| CAS Number | 359714-55-9 |
| Form | Solid |
| Solubility (25°C) | DMSO 100 mg/mL (ultrasonic) |
| Storage | 4°C, protect from light |
| Related MAGL Products |
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| JZL184
JZL 184 is the first selective inhibitor of monoacylglycerol lipase (MAGL) with IC50 of 8 nM. |
| JZL 195
JZL195 is an effective FAAH and MAGL inhibitor with IC50 of 2 nM and 4 nM, respectively. |
| JW 642
Jw642 is a highly effective selective monoacylglycerol lipase (MAGL) inhibitor with IC50 of 7.6 nM, 14 nM and 3.7 nM in mouse, rat and human meninges, respectively. |
| MJN110
MJN110 is an orally effective and selective inhibitor of monacylglycerol lipase (MAGL) with IC50 of 9.1 nM and 2.1 nM against hMAGL and 2-arachidonic triglyceride (2-AG), respectively. It has strong anti-hyperalgesia activity. |
| JJKK-048
JJKK-048 is a cell penetrant ultrapotent and highly selective inhibitor of monoacylglycerol lipase (MAGL) that exhibits a low cross-reactivity with other endocannabinoid targets. |
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