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Mafenide Acetate is used to treat severe burns. Mafenide acetate is a topical agent used routinely for these patients, but it has some disadvantages including painful application and allergic rash. 5% mafenide acetate/amphotericin B (2 mcg/ml) solution, applied to excised and grafted burn wounds, does not produce clinically relevant serum levels of amphotericin B. In honey-dressed wounds, early subsidence of acute inflammatory changes, better control of infection, and quicker wound healing were observed, while in mafenide acetate treated wounds a sustained inflammatory reaction was noted even on epithelialization.
| Molecular Weight | 246.28 |
| Formula | C9H14N2O4S |
| CAS Number | 13009-99-9 |
| Form | Solid |
| Solubility (25°C) | DMSO |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
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