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Lycorine is a natural alkaloid extracted from the Amaryllidaceae plant. Lycorine is a potent and orally active SCAP inhibitor with a Kd value 15.24 nM. Lycorine downregulates the SCAP protein level without changing its transcription. Lycorine is also a melanoma vasculogenic inhibitor. Lycorine can be used for the study of prostate cancer and metabolic diseases.
| Molecular Weight | 287.31 |
| CAS Number | 476-28-8 |
| Solubility (25°C) | DMSO 25 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[1] Na Li, et al. In Vitro Inhibition of Alphaviruses by Lycorine
[2] Shixue Zhao, et al. Antifungal effects of lycorine on Botrytis cinerea and possible mechanisms
[3] Strahil Berkov, et al. GC-MS of some lycorine-type Amaryllidaceae alkaloids
[5] Mridul Roy, et al. Lycorine: A prospective natural lead for anticancer drug discovery
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