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LY500307 potently binds both ERα and ERβ with Ki value of 2.68 nM and 0.19 nM. LY500307 displays potent inhibition toward ERβ with EC50 of 0.66 nM and shows full agonist function in estrogen receptor beta (ERbeta) in vitro assays (>90% relative efficacy).
| Molecular Weight | 282.33 |
| Formula | C18H18O3 |
| CAS Number | 533884-09-2 |
| Solubility (25°C) | DMSO 50 mg/mL Ethanol 50 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
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