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LY367385 hydrochloride is a highly selective and potent mGluR1a antagonist, with an IC50 of 8.8 μM for inhibiting of quisqualate-induced phosphoinositide (PI) hydrolysis, compared with >100 μM for mGlu5a.
| Molecular Weight | 245.66 |
| Formula | C10H12ClNO4 |
| CAS Number | 2829282-00-8 |
| Form | Solid |
| Solubility (25°C) | DMSO 100 mg/mL Water 10 mg/mL |
| Storage | 4°C, dry, sealed |
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