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LY3009120 (DP-4978) is a pan RAF inhibitor which inhibits BRAFV600E, BRAFWT and CRAFWT with IC50s of 5.8, 9.1 and 15 nM, respectively.
| Molecular Weight | 424.51 |
| CAS Number | 1454682-72-4 |
| Solubility (25°C) | DMSO ≥ 38 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[5] Robert Roskoski Jr. Targeting oncogenic Raf protein-serine/threonine kinases in human cancers
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