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LY 272015 hydrochloride is a high affinity 5-HT2B receptor antagonist that displays selectivity over 5-HT2A and 5-HT2C receptors (Ki values are 0.75, 21.63 and 28.7 nM for 5-HT2B, 5-HT2C and 5-HT2A receptors respectively). Orally active.
| Molecular Weight | 372.89 |
| Formula | C21H24N2O2.HCl |
| CAS Number | 172895-15-7 |
| Solubility (25°C) | DMSO 37.29 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
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