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Non-peptide CRF1 corticotrophin-releasing factor antagonist. Ki = 0.68 nM; blocks ethanol-induced effects as well as CRF effects in mice, suggesting a possible therapeutic target for the treatment of stress-induced alcohol drinking.
| Molecular Weight | 431.01 |
| Formula | C24H35ClN4O |
| CAS Number | 276890-57-4 |
| Solubility (25°C) | DMSO: ~10 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
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