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Lurtotecan

Cat. No. M28541

All AbMole products are for research use only, cannot be used for human consumption.

Lurtotecan Structure
Synonym:

GI147211; OSI-211

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Quality Control & Documentation
Biological Activity

Lurtotecan (GI147211; OSI-211), a semisynthetic Camptothecin analog, is a topoisomerase I inhibitor. Lurtotecan has anticancer effects.

Chemical Information
Molecular Weight 518.56
Formula C28H30N4O6
CAS Number 149882-10-0
Form Solid
Solubility (25°C) DMSO 4.33 mg/mL (ultrasonic)
Storage -20°C, protect from light, dry, sealed
References

[1] Diederik F S Kehrer, et al. J Clin Oncol. Phase I and pharmacologic study of liposomal lurtotecan, NX 211: urinary excretion predicts hematologic toxicity

[2] J P Desjardins, et al. Anticancer Drugs. Biodistribution of NX211, liposomal lurtotecan, in tumor-bearing mice

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  Catalog
Abmole Inhibitor Catalog




Keywords: Lurtotecan, GI147211; OSI-211 supplier, Topoisomerase, inhibitors, activators

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