All AbMole products are for research use only, cannot be used for human consumption.
Lumateperone (ITI-007) is a 5-HT2A receptor antagonist (Ki = 0.54 nM), a partial agonist of presynaptic D2 receptors and an antagonist of postsynaptic D2 receptors (Ki = 32 nM), and a dopamine D1 receptor modulator. Lumateperone has anticancer activity and can also be used in studies of psychiatric disorders such as schizophrenia.
| Molecular Weight | 393.5 |
| Formula | C24H28FN3O |
| CAS Number | 313368-91-1 |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
[1] No authors listed. Lumateperone
[2] Amber Edinoff, et al. Psychopharmacol Bull. Lumateperone for the Treatment of Schizophrenia
| Related Dopamine Receptor Products |
|---|
| Nepicastat hydrochloride
Nepicastat hydrochloride is a potent and selective inhibitor of both bovine and human dopamine-β-hydroxylase with IC50 of 8.5 nM and 9 nM, respectively. |
| Naxagolide
Naxagolide (Dopazinol) is a very potent and selective D2 agonist. |
| Alizapride hydrochloride
Alizapride hydrochloride is a dopamine receptor antagonist used for the theropy of nausea and vomiting. |
| Azaperone
Azaperone is a pyridinylpiperazine and butyrophenone neuroleptic compound with sedative and antiemetic effects, which is used mainly as a tranquilizer in veterinary medicine. |
| Benztropine mesylate
Benztropine is a dopamine transporter (DAT) inhibitor with IC50 of 118 nM. Benztropine mesylate is a human D2 dopamine receptor allosteric antagonist. Benztropine mesylate also has anti-CSCs (cancer stem cells) effects. Benztropine mesylate is also an anti-histamine agent and a dopamine re-uptake inhibitor. |
All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.
Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2026 AbMole BioScience. All Rights Reserved.
