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Lufotrelvir

Cat. No. M10872

All AbMole products are for research use only, cannot be used for human consumption.

Lufotrelvir Structure

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Quality Control & Documentation
Biological Activity

PF-07304814 IS A PHOSPHATE PRODRUG FOR PF-00835231 THAT BINDS AND INHIBITS SARS-CoV-2 3CLpro Active, Ki is 174 nM.

Chemical Information
Molecular Weight 552.51
Formula C24H33N4O9P
CAS Number 2468015-78-1
Solubility (25°C) DMSO ≥ 60 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Britton Boras, et al. Nat Commun. Preclinical characterization of an intravenous coronavirus 3CL protease inhibitor for the potential treatment of COVID19

[2] Elie Dolgin. Nature. The race for antiviral drugs to beat COVID - and the next pandemic

[3] Mohammad Hassan Baig, et al. Molecules. Is PF-00835231 a Pan-SARS-CoV-2 Mpro Inhibitor? A Comparative Study

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Keywords: Lufotrelvir supplier, inhibitors, activators

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