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Lu AA 47070 is a potent and selective precursor compound of adenosine A2A receptor antagonists with Ki values of 5.9, 260, 410 and <10,000 nM for A2A, A2B, A1 and A3 receptors, respectively. Reversal of Parkinson's dyskinesia and motivational effects by dopamine D2 receptor blockade in rats. Oral bioavailability.
| Molecular Weight | 463.39 |
| Formula | C17H20F2N3O6PS |
| CAS Number | 913842-25-8 |
| Solubility (25°C) | DMSO 46.34 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
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