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Lofexidine hydrochloride is an α2A-AR (adrenoceptor) agonist. Lofexidine inhibits the release of norepinephrine in the central and peripheral nervous system, thereby reducing some of the withdrawal symptoms.
| Molecular Weight | 295.59 |
| Formula | C11H12Cl2N2O.HCl |
| CAS Number | 21498-08-8 |
| Solubility (25°C) | DMSO 90 mg/mL Water 90 mg/mL |
| Storage | -20°C, dry, sealed |
[1] A Benjamin Srivastava, et al. New directions in the treatment of opioid withdrawal
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