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Lobeline (α-Lobeline; L-Lobeline), a lipophilic alkaloidal, is a nicotinic receptor agonist. Lobeline inhibits d-methamphetamine self-administration with no dopaminergic toxicity. Lobeline rescues d-amphetamine abuse induced addictive effect. Lobeline increases dopamine (DA) release by inhibiting DA uptake into synaptic vesicles, and altering presynaptic DA storage.
| Molecular Weight | 337.46 |
| Formula | C22H27NO2 |
| CAS Number | 90-69-7 |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
[3] Lindsay F Stead, et al. Cochrane Database Syst Rev. Lobeline for smoking cessation
[5] L F Stead, et al. Cochrane Database Syst Rev. Lobeline for smoking cessation
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