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Lipopolysaccharides

Cat. No. M9524

All AbMole products are for research use only, cannot be used for human consumption.

Lipopolysaccharides Structure
Synonym:

LPS

Size Price Availability Quantity
5mg USD 90 In stock
10mg USD 160 In stock
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Quality Control & Documentation
  • Purity: Potency ≥ 500000 EU/mg
  • COA
  • MSDS
Biological Activity

Lipopolysaccharides (LPS) is an endotoxin derived from the outer leaflet of the outer membrane of Gram-negative bacteria. Lipopolysaccharide is a highly immunogenic antigen which can enhance immune responses. This product is derived from Escherichia coli O55:B5. Its potency is more than 500,000 EU/mg.

Product Citations
Protocol (for reference only)
Cell Experiment
Cell lines CD8+ T cells
Preparation method Lymph node CD8+ T cells were purified cells by negative selection. The purified cells (2×10^6/mL) were cultured for 3 days in the presence of immobilised anti-CD3 antibody+IL-12 with or without LPS (5 μg/mL) or BLP (2 μg/mL) for a further 3 days.
Concentrations 5 μg/mL
Incubation time 3 days
Animal Experiment
Animal models C57BL/6 male mice acute lung injury model
Formulation Saline
Dosages 10 mg/kg
Administration Intratracheally administered
Chemical Information
Solubility (25°C) Water ≥ 5 mg/mL
Storage 2-8°C, protect from light, sealed
References

[1] Hai-Ping Zhu, et al. Mol Med Rep. Regulatory mechanism of NOV/CCN3 in the inflammation and apoptosis of lung epithelial alveolar cells upon lipopolysaccharide stimulation

[2] Lei Yang, et al. Am J Transl Res. Resveratrol alleviates sepsis-induced acute lung injury by suppressing inflammation and apoptosis of alveolar macrophage cells

[3] H T L Lai, et al. Poult Sci. Effects of Repeated Intratracheally Administered Lipopolysaccharide on Primary and Secondary Specific Antibody Responses and on Body Weight Gain of Broilers.

[4] D S Kabanov, et al. Biochemistry (Mosc). Structural Analysis of Lipopolysaccharides From Gram-negative Bacteria.

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Keywords: Lipopolysaccharides, LPS supplier, Animal Modeling, inhibitors, activators

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