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Linoleamide

Cat. No. M8754

All AbMole products are for research use only, cannot be used for human consumption.

Linoleamide Structure

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Biological Activity

亚油酰胺是一种内源性原代脂肪酸酰胺 （PFAM） 信号脂质，可调节细胞内 Ca2+ 稳态。它已被证明可以抑制SPCA2，这是一种高尔基体分泌途径Ca（2 +）-ATP酶，可运输Ca2 +和Mn2 +的离子，并且还抑制SPCA1a和三种sarco（endo）等离子体网Ca2 + -ATP酶（SERCA）泵亚型的Ca2 + -ATP酶活性。它被认为参与各种生物活动，包括睡眠调节。

Chemical Information
Molecular Weight 279.46
Formula C18H33常开
CAS Number 3999-01-7
Solubility (25°C) DMSO: 2 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Nalin Singh, et al. N-Benzyl-linoleamide, a Constituent of Lepidium meyenii (Maca), Is an Orally Bioavailable Soluble Epoxide Hydrolase Inhibitor That Alleviates Inflammatory Pain

[2] Sachiko Yamamoto, et al. Inhibitory action of linoleamide and oleamide toward sarco/endoplasmic reticulum Ca 2+-ATPase

[3] Haifa Almukadi, et al. The macamide N-3-methoxybenzyl-linoleamide is a time-dependent fatty acid amide hydrolase (FAAH) inhibitor

[4] T C Jenkins, et al. The biohydrogenation of linoleamide in vitro and its effects on linoleic acid concentration in duodenal contents of sheep

[5] J K Huang, et al. Linoleamide, a brain lipid that induces sleep, increases cytosolic Ca2+ levels in MDCK renal tubular cells

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Keywords: Linoleamide supplier, inhibitors, activators

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