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Licostinel

Cat. No. M43058

All AbMole products are for research use only, cannot be used for human consumption.

Licostinel Structure

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Quality Control & Documentation
Biological Activity

Licostinel (ACEA-1021) is a glycine receptor antagonist (IC50: 59 nM).

Chemical Information
Molecular Weight 276.03
Formula C8H3Cl2N3O4
CAS Number 153504-81-5
Form Solid
Solubility (25°C) DMSO 10 mg/mL (ultrasonic and warming)
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Margaret A Petty et al. Eur J Pharmacol. In vivo neuroprotective effects of ACEA 1021 confirmed by magnetic resonance imaging in ischemic stroke

[2] Zhang-Lin Zhou et al. Bioorg Med Chem. Synthesis and SAR of novel di- and trisubstituted 1,4-dihydroquinoxaline-2,3-diones related to licostinel (Acea 1021) as NMDA/glycine site antagonists

[3] No authors listed. Drugs R D. Licostinel. ACEA 1021

[4] G W Albers et al. Stroke. Dose escalation study of the NMDA glycine-site antagonist licostinel in acute ischemic stroke

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Keywords: Licostinel supplier, inhibitors, activators

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