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Licochalcone A is a chalconoid, a type of natural phenols. It can be isolated from root of Glycyrrhiza glabra (liquorice) or Glycyrrhiza inflata.
| Cell Experiment | |
|---|---|
| Cell lines | Human bladder carcinoma cells (T24 and EJ cells) |
| Preparation method | Cells in logarithmic growth phase were seeded into 6-well plates at a density of 6 × 10^4 cells/well. One day after seeding, 3 wells were taken to calculate the number of cells as the starting cell number, then LCB was added in three replicates of 0 µM, 5 µM, 10 µM, 20 µM for each cell population. Trypan blue staining was performed once daily since the 1st day of culture, and the viable cells in 3 wells of each group were counted for five consecutive days. |
| Concentrations | 0 µM, 5 µM, 10 µM, 20 µM |
| Incubation time | 5 days |
| Animal Experiment | |
|---|---|
| Animal models | Kunming mice |
| Formulation | - |
| Dosages | 25 mg/kg/day |
| Administration | Intragastrically |
| Molecular Weight | 286.28 |
| Formula | C16H14O5 |
| CAS Number | 58749-23-8 |
| Solubility (25°C) | 10 mM in DMSO |
| Storage | 2-8°C, dry, sealed, protect from light |
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