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LHF-535 

Cat. No. M28473

All AbMole products are for research use only, cannot be used for human consumption.

LHF-535  Structure

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Quality Control & Documentation
Biological Activity

LHF-535 is an antiviral agent with EC50 values of <1 μM, <1 μM, <1 μM, and 1-10 μM for Lassa, Machupo, Junin, and VSVg virus, respectively.

Chemical Information
Molecular Weight 412.52
Formula C27H28N2O2
CAS Number 1450929-77-7
Form Solid
Solubility (25°C) DMSO 90 mg/mL (ultrasonic)
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Kathleen A Cashman, et al. Sci Rep. Lassa antiviral LHF-535 protects guinea pigs from lethal challenge

[2] Sean M Amberg, et al. Antimicrob Agents Chemother. Safety and Pharmacokinetics of LHF-535, a Potential Treatment for Lassa Fever, in Healthy Adults

[3] Ikenna G Madu, et al. PLoS Pathog. A potent Lassa virus antiviral targets an arenavirus virulence determinant

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Keywords: LHF-535  supplier, Anti-infection, inhibitors, activators

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