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Levonadifloxacin

Cat. No. M28588

All AbMole products are for research use only, cannot be used for human consumption.

Levonadifloxacin Structure
Synonym:

(S)-(-)-Nadifloxacin; WCK 771

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Quality Control & Documentation
Biological Activity

Levonadifloxacin ((S)-(-)-Nadifloxacin; WCK 771) is a broad-spectrum anti-staphylococcal agent. Levonadifloxacin shows antibacterial activity against Methicillin-susceptible Staphylococcus aureus (MSSA) and Methicillin-resistant S. aureus (MRSA) strains, with a reduction of which phagocytized in THP-1 monocytes.

Chemical Information
Molecular Weight 360.38
Formula C19H21FN2O4
CAS Number 154357-42-3
Form Solid
Solubility (25°C) DMSO 125 mg/mL (ultrasonic)
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Yatin Mehta, et al. Crit Care Res Pract. Meeting the Unmet Need in the Management of MDR Gram-Positive Infections with Oral Bactericidal Agent Levonadifloxacin

[2] Balaji Veeraraghavan, et al. Indian J Med Microbiol. India-discovered levonadifloxacin & alalevonadifloxacin: A review on susceptibility testing methods, CLSI quality control and breakpoints along with a brief account of their emerging therapeutic profile as a novel standard-of-care

[3] Charul Lautre, et al. Crit Rev Anal Chem. Chemistry, Biological Properties and Analytical Methods of Levonadifloxacin: A Review

[4] Yamuna Devi Bakthavatchalam, et al. J Antimicrob Chemother. Levonadifloxacin, a recently approved benzoquinolizine fluoroquinolone, exhibits potent in vitro activity against contemporary Staphylococcus aureus isolates and Bengal Bay clone isolates collected from a large Indian tertiary care hospital

[5] Sachin S Bhagwat, et al. Drug Des Devel Ther. Levonadifloxacin, a Novel Broad-Spectrum Anti-MRSA Benzoquinolizine Quinolone Agent: Review of Current Evidence

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Keywords: Levonadifloxacin, (S)-(-)-Nadifloxacin; WCK 771 supplier, Antibiotic, inhibitors, activators

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