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Levetiracetam

Cat. No. M2257

All AbMole products are for research use only, cannot be used for human consumption.

Levetiracetam Structure
Synonym:

Keppra; UCB L059

Size Price Availability Quantity
Free Sample (0.5-1 mg)  USD 0 In stock
10mg USD 20 In stock
50mg USD 60 In stock
100mg USD 100 In stock
500mg USD 280 In stock
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Quality Control & Documentation
Biological Activity

Levetiracetam (UCB L059) is an antiepileptic, it is also a selective M2 muscarinic acetylcholine receptors (mAChR) inhibitor. Levetiracetam displays potent seizure protection in animal models of chronic epilepsy but lacks activity in acute seizure models. Levetiracetam binds synaptic vesicle protein 2A (SV2A).

Chemical Information
Molecular Weight 170.21
Formula C8H14N2O2
CAS Number 102767-28-2
Solubility (25°C) DMSO ≥ 30 mg/mL
Water ≥ 30 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Anthony Marson, et al. The SANAD II study of the effectiveness and cost-effectiveness of valproate versus levetiracetam for newly diagnosed generalised and unclassifiable epilepsy: an open-label, non-inferiority, multicentre, phase 4, randomised controlled trial

[2] Cynthia Sharpe, et al. Levetiracetam Versus Phenobarbital for Neonatal Seizures: A Randomized Controlled Trial

[3] James M Chamberlain, et al. Efficacy of levetiracetam, fosphenytoin, and valproate for established status epilepticus by age group (ESETT): a double-blind, responsive-adaptive, randomised controlled trial

[4] Mark D Lyttle, et al. Levetiracetam versus phenytoin for second-line treatment of paediatric convulsive status epilepticus (EcLiPSE): a multicentre, open-label, randomised trial

[5] Paul Howard, et al. Levetiracetam

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Keywords: Levetiracetam, Keppra; UCB L059 supplier, AChR/AChE, inhibitors, activators

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