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Leronlimab

Cat. No. M25245

All AbMole products are for research use only, cannot be used for human consumption.

Leronlimab Structure
Synonym:

PRO 140

Price and Availability

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Quality Control & Documentation
Biological Activity

Leronlimab (PRO 140) is a humanized IgG4 anti-CCR5 monoclonal antibody. Leronlimab inhibits CCR5-mediated HIV-1 viral and lung metastasis in mouse tumor models. Leronlimab can be used for the research of HIV nonalcoholic steatohepatitis (NASH) and cancer.

Chemical Information
CAS Number 674782-26-4
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
References

[1] Xuanmao Jiao, et al. Breast Cancer Res. Leronlimab, a humanized monoclonal antibody to CCR5, blocks breast cancer cellular metastasis and enhances cell death induced by DNA damaging chemotherapy

[2] Hélène Kaplon, et al. MAbs. Antibodies to watch in 2021

[3] Miao Miao, et al. Expert Opin Drug Metab Toxicol. Clinical significance of chemokine receptor antagonists

[4] Hélène Kaplon, et al. MAbs. Antibodies to watch in 2020

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  Catalog
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Keywords: Leronlimab, PRO 140 supplier, CCR, inhibitors, activators

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