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Leptomycin B

Cat. No. M6903

All AbMole products are for research use only, cannot be used for human consumption.

Leptomycin B Structure
Synonym:

CI 940; LMB

Size Price Availability Quantity
1mg USD 200 In stock
2mg USD 300 In stock
5mg USD 600 In stock
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Quality Control & Documentation
Biological Activity

Leptomycin B (CI 940;  LMB (LMB) is a protein exit nuclear transport inhibitor. Leptomycin deactivates CRM1/exportin 1 by covalent modification at cysteine residues. Leptomycin B is a potent antifungal antibiotic that blocks the eukaryotic cell cycle.

Chemical Information
Molecular Weight 540.74
Formula C33H48O6
CAS Number 87081-35-4
Form Melting point 41-44°C
Solubility (25°C) DMSO 90 mg/mL
Storage -20°C, sealed
References

[1] Zhang, et al. Nature. Targeting Bcr-Abl by combining allosteric with ATP-binding-site inhibitors.

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Abmole Inhibitor Catalog




Keywords: Leptomycin B, CI 940; LMB supplier, Antibiotic, inhibitors, activators

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