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Lenalidomide (Revlimid, CC-5013) is a TNF-α secretion inhibitor with IC50 of 13 nM.
| Molecular Weight | 268.27 |
| Formula | C13H14N3O3.5 |
| CAS Number | 847871-99-2 |
| Solubility (25°C) | 10 mM in DMSO |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Related TNF Receptor Products |
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| Lenalidomide
Lenalidomide is a thalidomide analog known to display TNF-α secretion inhibition and possesses immunomodulatory properties. |
| Atrosab
Atrosab is a humanized IgG1 antagonistic anti-TNFR1 antibody. Atrosab inhibits TNF-mediated Apoptosis induction and IL-6 and IL-8 production. Atrosab reduces neurological deficits. |
| Infliximab
Infliximab is a purified, recombinant DNA-derived chimeric human-mouse IgG monoclonal antibody that blocks TNF-α interaction with TNF-α receptor 1 (TNFR1) and TNFR2. For the treatment of autoimmune diseases. Infliximab is available in BALB/ C or C57/Bl6 mice. |
| Mesaconitine
Mesaconitine is the main active ingredient of Aconitum and has many pharmaceutical effects. |
| Hypaconitine
Hypaconitine is a highly toxic natural active ingredient isolated from aconitum species, which is widely used to study rheumatism. |
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