All AbMole products are for research use only, cannot be used for human consumption.
LEM-14 is a potent and selective NSD2 inhibitor with an IC50 of 132 µM. LEM-14 has very weak activitv against NSD1 and has no activity against NSD3. LEM-14 combined with ionizing radiation (IR) enhances the apoptosis rate and reduces the colony-formation ability of CRC cells. LEM-14 exhibits enhanced anti-tumor efficacy in Balb/c nude mice bearing LoVo cell xenografts when combined with ionizing radiation.
| Molecular Weight | 478.56 |
| Formula | C25H26N4O4S |
| CAS Number | 1814881-70-3 |
| Form | Solid |
| Solubility (25°C) | DMSO 50 mg/mL |
| Storage | Powder -20°C |
| Related Histone Methyltransferase Products |
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| EPZ004777 hydrochloride
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Products are for research use only. Not for human use. We do not sell to patients.
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