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LEI-106 

Cat. No. M28702

All AbMole products are for research use only, cannot be used for human consumption.

LEI-106  Structure

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Quality Control & Documentation
Biological Activity

LEI-106 is a potent, dual sn-1-Diacylglycerol lipase α (DAGL-α)/ABHD6 inhibitor with an IC50 of 18 nM for DAGL-α and a Ki of 0.8 μM for ABHD6. LEI-106 inhibits the hydrolysis of [14C]-sn-1-oleoyl-2-arachidonoyl-glycerol, the natural substrate of DAGL-α, with a Ki of 0.7 μM.

Chemical Information
Molecular Weight 481.56
Formula C26H27NO6S
CAS Number 1620582-23-1
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
References

[1] Freek J Janssen, et al. J Med Chem. Discovery of glycine sulfonamides as dual inhibitors of sn-1-diacylglycerol lipase α and α/β-hydrolase domain 6

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  Catalog
Abmole Inhibitor Catalog




Keywords: LEI-106  supplier, MAGL, inhibitors, activators

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