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LCS-1 is a superoxide dismutase 1 (SOD1) inhibitor. LCS-1 inhibited SOD1 activity with IC50 value of 1.07 μM. LCS-1 induces early and late apoptosis in multiple myeloma cells (MM.1S).
| Molecular Weight | 255.1 |
| Formula | C11H8Cl2N2O |
| CAS Number | 41931-13-9 |
| Solubility (25°C) | DMSO ≥ 40 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Related SOD Products |
|---|
| ATN-224
ATN-224 is an orally active superoxide dismutase 1 (SOD1) inhibitor. ATN-224 inhibits SOD1 activity with an IC50 of 17.5±3.7 nM on endothelial cells. |
| NUCC-0000323
NUCC-0000323 is a potent superoxide dismutase 1 (SOD1) inhibitor. NUCC-0000323 inhibits SOD1 expression. |
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